Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 8/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | AADAC | P22760 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653264 | 0.91 | SLC9A1 (0.41) | SLC9A1KCNH2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9018726 | 0.84 | SLC9A1 (0.50) | SLC9A1KCNH2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9018702 | 0.82 | PLAU (0.44) | SLC9A1KCNH2PLAU | |
| SCHEMBL9018661 | 0.82 | PLAU (0.44) | SLC9A1KCNH2PLAU | |
| SCHEMBL9018736 | 0.81 | SLC9A1 (0.40) | SLC9A1PLAUALDH1A1LMNA | |
| SCHEMBL9018681 | 0.78 | SLC9A1 (0.54) | SLC9A1KCNH2 | |
| SCHEMBL8610045 | 0.77 | SLC9A1 (0.48) | SLC9A1KCNH2LMNASMN1; SMN2 | |
| SCHEMBL24525434 | 0.76 | NOTUM (0.50) | KCNH2ALDH1A1LMNACYP3A4AR | |
| SCHEMBL9018719 | 0.76 | AKR1B1 (0.46) | SLC9A1PLAUALDH1A1LMNACYP3A4 | |
| SCHEMBL9018678 | 0.76 | SLC9A1 (0.45) | SLC9A1KCNH2PLAUCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743301-A2 | Benzoylguanidines containing fluorine | MERCK PATENT GmbH (DE) | 1996-11-20 | — | — | EP | disclosed |