Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476919 | 0.93 | LMNA (0.69) | LMNAPOLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3034180 | 0.84 | HPGD (0.58) | ALDH1A1HPGDRAB9A | |
| SCHEMBL2093177 | 0.80 | MAPT (0.71) | LMNAPOLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL14817806 | 0.80 | ALDH1A1 (0.65) | LMNAPOLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2093176 | 0.79 | MAPT (0.69) | LMNAPOLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8334831 | 0.77 | KDM4E (0.69) | LMNAPOLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6474649 | 0.77 | MAPT (0.67) | LMNAPOLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10890405 | 0.77 | KDM4E (0.51) | LMNAPOLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3612815 | 0.77 | MEN1 (0.67) | LMNAPOLBMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30623497 | 0.77 | MEN1 (0.67) | LMNAPOLBMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445926-B1 | Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation | MILLIKEN RES CORP (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5240464-A | Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation | MILLIKEN RESEARCH CORPORATION (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0445926-A2 | Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation | MILLIKEN RESEARCH CORPORATION (US) | 1991-09-11 | — | — | EP | disclosed |