Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5229558 | 0.75 | HTT (0.58) | POLBLMNARECQLKDM4EGLA | |
| SCHEMBL11574413 | 0.75 | PPARG (0.54) | DRD2DRD4LMNAKDM4EHSD17B10 | |
| SCHEMBL11875504 | 0.73 | DRD2 (0.46) | DRD2DRD4LMNARECQLALDH1A1 | |
| SCHEMBL11676661 | 0.72 | F2 (0.54) | DRD2DRD4F2ALDH1A1LTA4H | |
| SCHEMBL11422634 | 0.70 | ALDH1A1 (0.44) | DRD2DRD4LMNAKDM4EGLA | |
| SCHEMBL11676462 | 0.70 | MAPT (0.54) | DRD2DRD4LMNAKDM4EALDH1A1 | |
| SCHEMBL2063136 | 0.69 | DRD2 (0.72) | DRD2DRD4LMNAKDM4EF2 | |
| SCHEMBL5686017 | 0.69 | DRD2 (0.72) | DRD2DRD4LMNAKDM4EF2 | |
| SCHEMBL9018838 | 0.69 | DRD2 (0.55) | DRD2DRD4F2HTTHTR7 | |
| SCHEMBL11593992 | 0.69 | MAPK1 (0.48) | DRD2DRD4LMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445926-B1 | Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation | MILLIKEN RES CORP (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5240464-A | Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation | MILLIKEN RESEARCH CORPORATION (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0445926-A2 | Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation | MILLIKEN RESEARCH CORPORATION (US) | 1991-09-11 | — | — | EP | disclosed |