Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 6/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17249877 | 0.97 | ADRA1B (0.44) | ADRA1BPIK3CDKMT2AMEN1PKM | |
| SCHEMBL19102068 | 0.95 | ADRA1B (0.43) | ADRA1BPIK3CDKMT2AMEN1PKM | |
| SCHEMBL17253543 | 0.95 | ADRA1B (0.43) | ADRA1BPIK3CDKMT2AMEN1PKM | |
| SCHEMBL17285844 | 0.89 | LMNA (0.45) | ADRA1BPIK3CDKMT2AMEN1PKM | |
| SCHEMBL17285845 | 0.83 | PIK3CD (0.47) | ADRA1BPIK3CDKMT2AMEN1PKM | |
| SCHEMBL9018951 | 0.82 | PIK3CD (0.50) | ADRA1BPIK3CDKMT2AMEN1PKM | |
| SCHEMBL9018974 | 0.80 | PIK3CD (0.51) | ADRA1BPIK3CDKMT2AMEN1PKM | |
| SCHEMBL989008 | 0.80 | PIK3CD (0.52) | ADRA1BPIK3CDKMT2AMEN1PKM | |
| SCHEMBL19514132 | 0.80 | PIK3CD (0.52) | ADRA1BPIK3CDKMT2AMEN1PKM | |
| SCHEMBL31632694 | 0.80 | PIK3CD (0.52) | ADRA1BPIK3CDKMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691954-A4 | ASYMMETRICAL POLYPYRROLIDONYL COMPOUNDS HAVING A WIDE LIQUID RANGE | ISP INVESTMENTS INC (US) | 1996-04-24 | — | — | EP | disclosed |
| EP-0691954-A1 | ASYMMETRICAL POLYPYRROLIDONYL COMPOUNDS HAVING A WIDE LIQUID RANGE | ISP INVESTMENTS INC. (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994020462-A1 | ASYMMETRICAL POLYPYRROLIDONYL COMPOUNDS HAVING A WIDE LIQUID RANGE | ISP INVESTMENTS INC. (US) | 1994-09-15 | — | — | WO | disclosed |
| US-5326880-A | Asymmetrical polypyrrolidonyl compounds having a wide liquid range | ISP INVESTMENTS INC. (US) | 1994-07-05 | — | — | US | disclosed |