Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4872353 | 0.87 | TSHR (0.72) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL1500536 | 0.86 | TSHR (0.51) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL1247034 | 0.84 | TSHR (0.61) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL6413351 | 0.83 | GAA (0.54) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL10727676 | 0.81 | TSHR (0.54) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL11464001 | 0.81 | TSHR (0.54) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL3880496 | 0.81 | TSHR (0.54) | TSHRALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL9018836 | 0.81 | HSP90AA1 (0.43) | MAPTHIF1AHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL28291431 | 0.81 | CA2 (0.62) | TSHRCA1CA2CA9LMNA | |
| SCHEMBL5188628 | 0.80 | HTR2A (0.46) | ALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543573-A | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0462456-B1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0462456-A1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |