Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 13/20 | 0.62 |
| ▸ | CA1 | P00915 | 11/20 | 0.62 |
| ▸ | CA9 | Q16790 | 9/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 6/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9018905 | 0.81 | TSHR (0.54) | CA2CA1CA9TSHRLMNA | |
| SCHEMBL5677878 | 0.80 | CA2 (0.72) | CA2CA1CA9CA12CA14 | |
| SCHEMBL1500536 | 0.75 | TSHR (0.51) | CA2CA1CA9TSHRLMNA | |
| SCHEMBL26134815 | 0.75 | TSHR (0.69) | CA2CA1CA9TSHRLMNA | |
| SCHEMBL10692906 | 0.74 | CA2 (0.61) | CA2CA1CA9CA12CA14 | |
| SCHEMBL4872353 | 0.74 | TSHR (0.72) | CA2CA1CA9TSHR | |
| SCHEMBL6024972 | 0.73 | CA2 (0.62) | CA2CA1CA9MAOACA12 | |
| SCHEMBL28423617 | 0.72 | TSHR (0.60) | TSHRLMNA | |
| SCHEMBL4663042 | 0.72 | KCNA5 (0.43) | CA2CA1CA9CA12CA14 | |
| SCHEMBL6272312 | 0.71 | TSHR (0.62) | CA2CA1CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574863-A | A kind of synthetic method of -4 ' of 2- amino-fluoro- benzophenone | 安徽省庆云医药股份有限公司 | 2019-04-05 | — | — | CN | claimed |