Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577031 | 1.00 | LTA4H (0.57) | LTA4HSRD5A2S1PR1CES2CES1 | |
| SCHEMBL7811168 | 0.92 | LMNA (0.62) | LTA4HSRD5A2S1PR1LMNAMAPK1 | |
| SCHEMBL7935395 | 0.92 | LMNA (0.58) | LTA4HSRD5A2S1PR1KMT2ALMNA | |
| SCHEMBL238259 | 0.85 | LTA4H (0.73) | LTA4HSRD5A2CES2CES1LMNA | |
| SCHEMBL8572071 | 0.85 | LTA4H (0.73) | LTA4HSRD5A2CES2CES1LMNA | |
| SCHEMBL1736339 | 0.85 | LTA4H (0.73) | LTA4HSRD5A2CES2CES1LMNA | |
| SCHEMBL7016563 | 0.84 | S1PR1 (0.57) | LTA4HS1PR1CES2CES1KMT2A | |
| SCHEMBL15199479 | 0.84 | LTA4H (0.55) | LTA4HS1PR1CES2CES1LMNA | |
| SCHEMBL7371911 | 0.83 | LTA4H (0.70) | LTA4HSRD5A2CES2CES1LMNA | |
| Hydrochloric Acid SCHEMBL27713233 | 0.83 | LTA4H (0.70) | LTA4HSRD5A2CES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543573-A | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| EP-0462456-B1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0462456-A1 | Hydrazinecarboxamide derivatives, a process for production thereof, and uses thereof | NIHON NOHYAKU CO., LTD. (JP) | 1991-12-27 | — | — | EP | disclosed |