Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682368 | 0.90 | DRD2 (0.57) | DRD2HTR1ADRD3 | |
| SCHEMBL29269190 | 0.87 | DRD2 (0.51) | DRD2HTR1AMAOAMAOBDRD3 | |
| SCHEMBL13253319 | 0.85 | MAOA (0.63) | DRD2HTR1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL7328900 | 0.84 | DRD2 (0.51) | DRD2HTR1ADRD3 | |
| Oxalic Acid SCHEMBL10445493 | 0.82 | HTT (0.55) | DRD2HTR1A | |
| SCHEMBL19200350 | 0.82 | DRD2 (0.50) | DRD2HTR1AMAOAMAOBDRD3 | |
| SCHEMBL10516302 | 0.81 | DRD2 (0.51) | DRD2HTR1ADRD3 | |
| SCHEMBL6929788 | 0.80 | CXCR4 (0.47) | DRD2MAOAMAOB | |
| SCHEMBL6925802 | 0.80 | CXCR4 (0.47) | DRD2MAOAMAOB | |
| SCHEMBL6435421 | 0.80 | CXCR4 (0.47) | DRD2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712387-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004713-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | THE UPJOHN COMPANY (US) | 1995-02-16 | — | — | WO | disclosed |