Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351414 | 0.97 | NFKB1 (0.47) | GSRNFKB1CA12CA1CA2 | |
| SCHEMBL11084535 | 0.94 | GSR (0.44) | GSRNFKB1CA12CA1CA2 | |
| SCHEMBL3792319 | 0.94 | DNM1 (0.50) | GSRNFKB1CA12CA1CA2 | |
| SCHEMBL7475389 | 0.94 | DNM1 (0.50) | GSRNFKB1CA12CA1CA2 | |
| SCHEMBL19328394 | 0.94 | DNM1 (0.50) | GSRNFKB1CA12CA1CA2 | |
| SCHEMBL11021472 | 0.94 | DNM1 (0.50) | GSRNFKB1CA12CA1CA2 | |
| SCHEMBL15208926 | 0.94 | NFKB1 (0.40) | GSRNFKB1CA12CA1CA2 | |
| SCHEMBL15208527 | 0.94 | GSR (0.42) | GSRNFKB1CA12CA1CA2 | |
| SCHEMBL350694 | 0.94 | NFKB1 (0.50) | GSRNFKB1CA12CA1CA2 | |
| SCHEMBL16696692 | 0.90 | DNM1 (0.53) | GSRNFKB1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691954-A4 | ASYMMETRICAL POLYPYRROLIDONYL COMPOUNDS HAVING A WIDE LIQUID RANGE | ISP INVESTMENTS INC (US) | 1996-04-24 | — | — | EP | disclosed |
| EP-0691954-A1 | ASYMMETRICAL POLYPYRROLIDONYL COMPOUNDS HAVING A WIDE LIQUID RANGE | ISP INVESTMENTS INC. (US) | 1996-01-17 | — | — | EP | disclosed |
| WO-1994020462-A1 | ASYMMETRICAL POLYPYRROLIDONYL COMPOUNDS HAVING A WIDE LIQUID RANGE | ISP INVESTMENTS INC. (US) | 1994-09-15 | — | — | WO | disclosed |
| US-5326880-A | Asymmetrical polypyrrolidonyl compounds having a wide liquid range | ISP INVESTMENTS INC. (US) | 1994-07-05 | — | — | US | disclosed |