⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019061 | 1.00 | — | — | |
| SCHEMBL9018977 | 1.00 | — | — | |
| SCHEMBL31519172 | 0.89 | — | — | |
| SCHEMBL6046236 | 0.86 | MEN1 (0.48) | — | |
| SCHEMBL4904318 | 0.83 | TSHR (0.39) | — | |
| Methacrylic Acid SCHEMBL10613526 | 0.82 | TGFBR1 (0.37) | — | |
| SCHEMBL1651709 | 0.82 | — | — | |
| SCHEMBL14544838 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL1524501 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL29044556 | 0.82 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240368063-A1 | PREPARATION METHOD, INTERMEDIATE COMPOUNDS, AND SYNTHESIS METHOD FOR A CLASS OF ANTHRACENE-DERIVED TOXINS IN ORGANIC CHEMISTRY | WUYAN PHARMACEUTICAL TECHNOLOGY (SHANGHAI) CO., LTD (CN) | 2024-11-07 | — | — | US | disclosed |
| CN-115650827-A | Preparation method, intermediate compound and synthesis method for anthracycline derivatives | 戊言医药科技（上海）有限公司 | 2023-01-31 | — | — | CN | disclosed |
| US-20090076258-A1 | Method for synthesizing oligosaccharides and glycosylation | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2009-03-19 | — | — | US | disclosed |
| EP-0434960-B1 | Chiral 1,5-diiodo-2-methoxy or benzyloxy intermediates | PHARMACIA SPA (IT) | 1996-09-18 | — | — | EP | disclosed |
| US-5304687-A | 1-alkoxy-2,2*-diiodo-diethyl ether which reacts with doxorubicin to yield anthrocycline antibiotics | FARMITALIA CARLO ERBA S.R.L. (IT) | 1994-04-19 | — | — | US | disclosed |
| EP-0434960-A1 | Chiral 1,5-diiodo-2-methoxy or benzyloxy intermediates | PHARMACIA S.p.A. (IT) | 1991-07-03 | — | — | EP | disclosed |
| WO-1991009046-A1 | MORPHOLINYL DERIVATIVES OF DOXORUBICIN AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1991-06-27 | — | — | WO | disclosed |