Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | OGT | O15294 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL9180562 | 0.94 | SMN1; SMN2 (0.40) | SMN1; SMN2OPRD1SLC22A1CCR2OGT | |
| SCHEMBL9019226 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2OPRD1OPRM1MEN1KMT2A | |
| SCHEMBL9019287 | 0.69 | CCR2 (0.59) | SMN1; SMN2SLC22A1CCR2ALDH1A1KDM4E | |
| SCHEMBL16644926 | 0.69 | SMN1; SMN2 (0.60) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3726123 | 0.69 | SMN1; SMN2 (0.60) | SMN1; SMN2OPRD1ALDH1A1MEN1KMT2A | |
| SCHEMBL14015971 | 0.69 | MTOR (0.52) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29103977 | 0.68 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL21535462 | 0.68 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL1174449 | 0.68 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1174179 | 0.68 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581167-B1 | Novel arylglycinamide derivatives and preparative processes therefor and their use for treatment of dysuria | KYORIN SEIYAKU KK (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5439919-A | Treatment of urinary incontinence | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| EP-0581167-A1 | Novel arylglycinamide derivatives and preparative processes therefor and their use for treatment of dysuria | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |