SCHEMBL9019287

SCHEMBL9019287

CCN(CC)CCNC(C(=O)NC(C)(C)C)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 3/20 0.59
SLC22A1 O15245 1/20 0.58
ALDH1A1 P00352 3/20 0.57
KDM4E B2RXH2 3/20 0.57
CTDSP1 Q9GZU7 1/20 0.56
GHSR Q92847 1/20 0.46
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
GPR88 Q9GZN0 1/20 0.43
MAPT P10636 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CYP3A4 P08684 1/20 0.43
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL9184503 0.94 CCR2 (0.54) CCR2SLC22A1ALDH1A1KDM4ECTDSP1
SCHEMBL6322016 0.82 SLC22A1 (0.62) CCR2SLC22A1ALDH1A1KDM4ECTDSP1
Camylofin SCHEMBL617472 0.73 SLC22A1 (1.00) CCR2SLC22A1ALDH1A1KDM4ECTDSP1
Camylofin SCHEMBL12481408 0.73 SLC22A1 (0.98) CCR2SLC22A1ALDH1A1KDM4ECTDSP1
Camylofin SCHEMBL10867839 0.73 SLC22A1 (0.98) CCR2SLC22A1ALDH1A1KDM4ECTDSP1
SCHEMBL9152364 0.71 MAPT (0.46) ALDH1A1KDM4EGPR88MAPTSMN1; SMN2
SCHEMBL9152358 0.71 MAPT (0.46) ALDH1A1KDM4EGPR88MAPTSMN1; SMN2
SCHEMBL10996034 0.70 CYP3A4 (0.58) CCR2SLC22A1ALDH1A1KDM4ELMNA
SCHEMBL13611896 0.70 GPR88 (0.49) ALDH1A1KDM4ELMNACYP1A2CYP2D6
SCHEMBL9019197 0.69 SMN1; SMN2 (0.45) CCR2SLC22A1ALDH1A1KDM4ECTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0581167-B1 Novel arylglycinamide derivatives and preparative processes therefor and their use for treatment of dysuria KYORIN SEIYAKU KK (JP) 1996-10-09 EP disclosed
US-5439919-A Treatment of urinary incontinence KYORIN PHARMACEUTICAL CO., LTD. (JP) 1995-08-08 US disclosed
EP-0581167-A1 Novel arylglycinamide derivatives and preparative processes therefor and their use for treatment of dysuria KYORIN PHARMACEUTICAL CO., LTD. (JP) 1994-02-02 EP disclosed