Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901864 | 0.91 | KARS1 (0.49) | IDH2SYK | |
| SCHEMBL1704715 | 0.86 | IDH2 (0.40) | IDH2SYK | |
| SCHEMBL1704492 | 0.84 | KARS1 (0.51) | IDH2SYK | |
| SCHEMBL901986 | 0.84 | SYK (0.50) | IDH2SYK | |
| SCHEMBL1704561 | 0.82 | KARS1 (0.55) | IDH2SYK | |
| SCHEMBL1704255 | 0.79 | KARS1 (0.52) | IDH2SYK | |
| SCHEMBL902758 | 0.79 | KARS1 (0.64) | SYK | |
| SCHEMBL1705304 | 0.76 | KARS1 (0.47) | SYK | |
| SCHEMBL1704269 | 0.74 | KARS1 (0.47) | — | |
| SCHEMBL901917 | 0.73 | KARS1 (0.53) | IDH2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2441755-A1 | Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors | Almirall, S.A. (ES) | 2012-04-18 | — | — | EP | disclosed |