Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19492022 | 0.86 | USP30 (0.35) | HDAC6HDAC1HDAC2CYP2D6CA1 | |
| SCHEMBL24824282 | 0.81 | CA1 (0.34) | HDAC6HDAC1HDAC2CYP2D6CA1 | |
| SCHEMBL646682 | 0.79 | MEN1 (0.33) | HDAC6HDAC1HDAC2CA1CA2 | |
| SCHEMBL30279497 | 0.79 | MEN1 (0.30) | — | |
| SCHEMBL20811333 | 0.78 | MEN1 (0.32) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL22221412 | 0.78 | MEN1 (0.32) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL503445 | 0.77 | HDAC6 (0.35) | HDAC6HDAC1HDAC2CYP2D6CA1 | |
| SCHEMBL5204515 | 0.76 | CA14 (0.39) | HDAC6HDAC1HDAC2CA1CA2 | |
| SCHEMBL643632 | 0.76 | AAK1 (0.35) | HDAC6HDAC1HDAC2CYP2D6CA1 | |
| SCHEMBL1028060 | 0.73 | POLB (0.45) | HDAC6HDAC1HDAC2CYP2D6CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581167-B1 | Novel arylglycinamide derivatives and preparative processes therefor and their use for treatment of dysuria | KYORIN SEIYAKU KK (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5439919-A | Treatment of urinary incontinence | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| EP-0581167-A1 | Novel arylglycinamide derivatives and preparative processes therefor and their use for treatment of dysuria | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1994-02-02 | — | — | EP | disclosed |