Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10895444 | 0.85 | MAPT (0.56) | MAPTTDP1LMNAPGRCYP3A4 | |
| Docebenone SCHEMBL522781 | 0.83 | MAPT (0.41) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL11093696 | 0.81 | MAPT (0.53) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL11101641 | 0.81 | MAPT (0.49) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL15519187 | 0.79 | PTPN7 (0.54) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL14684712 | 0.78 | MAPT (0.38) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL10892984 | 0.77 | MAPT (0.35) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL15517158 | 0.77 | TDP1 (0.39) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL15520246 | 0.77 | TDP1 (0.42) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL15518487 | 0.77 | TDP1 (0.45) | MAPTTDP1LMNAPGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103361-B1 | QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1986-01-29 | — | — | EP | claimed |
| US-4489096-A | ANTIASTHMA, ANTIALLERGEN | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-12-18 | — | — | US | claimed |
| EP-0103361-A1 | Quinone compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-03-21 | — | — | EP | claimed |
| US-5563129-A | Hydroquinone derivatives and intermediates for production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-08 | — | — | US | disclosed |
| US-5534639-A | Hydroquinone derivatives and intermediates for production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| US-5436359-A | Hydroquinone derivatives and intermediates for production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0560568-A2 | Hydroquinone derivatives and intermediates for production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
| EP-0103361-B1 | QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1986-01-29 | — | — | EP | disclosed |
| US-4489096-A | ANTIASTHMA, ANTIALLERGEN | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-12-18 | — | — | US | disclosed |
| EP-0103361-A1 | Quinone compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-03-21 | — | — | EP | disclosed |