Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093696 | 0.97 | MAPT (0.53) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL15518487 | 0.95 | TDP1 (0.45) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL15520246 | 0.89 | TDP1 (0.42) | MAPTTDP1LMNAPGRCYP3A4 | |
| Docebenone SCHEMBL522781 | 0.88 | MAPT (0.41) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL15517158 | 0.85 | TDP1 (0.39) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL11096677 | 0.85 | MAPT (0.62) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL2455425 | 0.83 | MAPT (0.66) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL13696967 | 0.83 | MAPT (0.66) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL8294278 | 0.83 | MAPT (0.66) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL14684716 | 0.83 | MAPT (0.66) | MAPTTDP1LMNAPGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170209393-A1 | BENZOQUINONE DERIVATIVES FOR TREATING OXIDATIVE STRESS DISORDERS | BIOELECTRON TECHNOLOGY CORPORATION | 2017-07-27 | — | — | US | claimed |
| US-9629815-B2 | Benzoquinone derivatives for treating oxidative stress disorders | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2017-04-25 | — | — | US | claimed |
| US-20150218079-A1 | BENZOQUINONE DERIVATIVES FOR TREATING OXIDATIVE STRESS DISORDERS | EDISON PHARMACEUTICALS, INC. (US) | 2015-08-06 | — | — | US | claimed |
| EP-2892515-A1 | BENZOQUINONE DERIVATIVES FOR TREATING OXIDATIVE STRESS DISORDERS | Edison Pharmaceuticals, Inc. (US) | 2015-07-15 | — | — | EP | claimed |
| WO-2014039917-A1 | BENZOQUINONE DERIVATIVES FOR TREATING OXIDATIVE STRESS DISORDERS | EDISON PHARMACEUTICALS, INC. (US) | 2014-03-13 | — | — | WO | claimed |
| US-20170209393-A1 | BENZOQUINONE DERIVATIVES FOR TREATING OXIDATIVE STRESS DISORDERS | BIOELECTRON TECHNOLOGY CORPORATION | 2017-07-27 | — | — | US | disclosed |
| US-9629815-B2 | Benzoquinone derivatives for treating oxidative stress disorders | BIOELECTRON TECHNOLOGY CORPORATION (US) | 2017-04-25 | — | — | US | disclosed |
| US-20150216820-A1 | QUINONE DERIVATIVES FOR USE IN THE MODULATION OF REDOX STATUS OF INDIVIDUALS | BIOELECTRON TECHNOLOGY CORPORATION | 2015-08-06 | — | — | US | disclosed |
| US-20150218079-A1 | BENZOQUINONE DERIVATIVES FOR TREATING OXIDATIVE STRESS DISORDERS | EDISON PHARMACEUTICALS, INC. (US) | 2015-08-06 | — | — | US | disclosed |
| EP-2892515-A1 | BENZOQUINONE DERIVATIVES FOR TREATING OXIDATIVE STRESS DISORDERS | Edison Pharmaceuticals, Inc. (US) | 2015-07-15 | — | — | EP | disclosed |
| EP-2892516-A1 | QUINONE DERIVATIVES FOR USE IN THE MODULATION OF REDOX STATUS OF INDIVIDUALS | Edison Pharmaceuticals, Inc. (US) | 2015-07-15 | — | — | EP | disclosed |
| WO-2014039917-A1 | BENZOQUINONE DERIVATIVES FOR TREATING OXIDATIVE STRESS DISORDERS | EDISON PHARMACEUTICALS, INC. (US) | 2014-03-13 | — | — | WO | disclosed |
| WO-2014039862-A1 | QUINONE DERIVATIVES FOR USE IN THE MODULATION OF REDOX STATUS OF INDIVIDUALS | EDISON PHARMACEUTICALS, INC. (US) | 2014-03-13 | — | — | WO | disclosed |
| EP-0038160-B1 | QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1984-09-19 | — | — | EP | disclosed |
| US-4393075-A | SLOW-REACTING-SUBSTANCE OF ANAPHYLAXIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170209393-A1 | BENZOQUINONE DERIVATIVES FOR TREATING OXIDATIVE STRESS DISORDERS | UQCRC1, TXN2, CYC1 | MAPT 1872/4885TDP1 778/4885LMNA 572/4885 |
| US-20150218079-A1 | BENZOQUINONE DERIVATIVES FOR TREATING OXIDATIVE STRESS DISORDERS | UQCRC1, CYC1, UQCRC2 | MAPT 2211/4885TDP1 686/4885LMNA 414/4885 |
| US-20150216820-A1 | QUINONE DERIVATIVES FOR USE IN THE MODULATION OF REDOX STATUS OF INDIVIDUALS | GSR, GLS, GPX4 | MAPT 3675/4885TDP1 1828/4885LMNA 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.