Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CASP1 | P29466 | 4/20 | 0.53 |
| ▸ | CASP7 | P55210 | 4/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019345 | 0.85 | ADORA3 (0.58) | ADORA3KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL9732997 | 0.81 | ADORA3 (0.64) | ADORA3KDM4EMAPTHSD17B10ALDH1A1 | |
| Kaempferol Tetraacetate SCHEMBL10379364 | 0.80 | ADORA3 (0.84) | ADORA3KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL9019328 | 0.77 | ADORA3 (0.49) | ADORA3KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL1664667 | 0.77 | ADORA3 (1.00) | ADORA3KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL15266926 | 0.77 | ADORA3 (0.79) | ADORA3KDM4EMAPTHSD17B10ALDH1A1 | |
| Pentaacetylquercetin SCHEMBL4064499 | 0.76 | ADORA3 (0.77) | ADORA3KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL15965556 | 0.76 | KDM4E (0.66) | ADORA3KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL10472254 | 0.75 | KDM4E (0.72) | ADORA3KDM4EMAPTHSD17B10ALDH1A1 | |
| SCHEMBL28377445 | 0.74 | ADORA3 (0.77) | ADORA3KDM4EMAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450588-B1 | Substituted 3-thia- or 3-oxa-alkyl flavones, process for their preparation, their application and drugs based on these compounds as well as intermediates | HOECHST AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| US-5173498-A | For treating arteriosclerosis or hypercholesterolemia | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-22 | — | — | US | disclosed |
| EP-0450588-A1 | Substituted 3-thia- or 3-oxa-alkyl flavones, process for their preparation, their application and drugs based on these compounds as well as intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |