Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.59 |
| ▸ | IKBKB | O14920 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28369886 | 0.89 | VKORC1 (0.65) | VKORC1IKBKBKMT2AKDM4ELMNA | |
| SCHEMBL28444444 | 0.88 | VKORC1 (0.67) | VKORC1IKBKBKMT2AKDM4ELMNA | |
| SCHEMBL28552754 | 0.88 | VKORC1 (0.67) | VKORC1IKBKBKMT2AKDM4ELMNA | |
| SCHEMBL7047705 | 0.83 | CYP3A4 (0.59) | VKORC1IKBKBKMT2AKDM4ELMNA | |
| SCHEMBL7047704 | 0.83 | IKBKB (0.59) | VKORC1IKBKBKMT2AKDM4EMEN1 | |
| SCHEMBL9019380 | 0.83 | DDR2 (0.60) | KMT2AKDM4ELMNAMEN1TP53 | |
| SCHEMBL30672824 | 0.82 | KMT2A (0.55) | KMT2AKDM4ELMNAMEN1TP53 | |
| SCHEMBL16924700 | 0.82 | VKORC1 (0.63) | VKORC1IKBKBKMT2AKDM4ELMNA | |
| SCHEMBL31319016 | 0.80 | ABCG2 (0.60) | KMT2AKDM4ELMNAMEN1TP53 | |
| SCHEMBL19846946 | 0.80 | KMT2A (0.64) | KMT2AKDM4ELMNAMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114796194-A | Application of DA adduct derived from Morus plant in preparation of beta-G inhibitor | 澳门大学 | 2022-07-29 | — | — | CN | claimed |
| CN-119258055-A | Composition for inhibiting oral pathogenic bacteria and application thereof | 大连医科大学附属第二医院 | 2025-01-07 | — | — | CN | disclosed |
| CN-118160721-A | Application of fulvol in inhibiting viroid in tomatoes | 贵州大学 | 2024-06-11 | — | — | CN | disclosed |
| CN-117491545-A | Method for extracting and quantitatively detecting content of cyclomorine from biological matrix | 温州医科大学附属第二医院（温州医科大学附属育英儿童医院） | 2024-02-02 | — | — | CN | disclosed |
| CN-116554515-A | Preparation method of oxidation-resistant packaging film for prepackaging aviation cutlery box | 浙江广厦建设职业技术大学 | 2023-08-08 | — | — | CN | disclosed |
| CN-116554515-A | Preparation method of oxidation-resistant packaging film for prepackaging aviation cutlery box | 浙江广厦建设职业技术大学 | 2023-08-08 | — | — | CN | disclosed |
| US-20230190852-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | UNIGEN, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| CN-112851615-B | Preparation of isopentenyl flavone and application of isopentenyl flavone as medicine for treating cervical cancer | 厦门大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-112851615-B | Preparation of isopentenyl flavone and application of isopentenyl flavone as medicine for treating cervical cancer | 厦门大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-112552309-B | Psoralen benzene sulfonate derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-03-14 | — | — | CN | disclosed |
| EP-1453827-A4 | METHODS FOR PREPARING AN ESTROGENIC PREPARATION AND ISOLATED ESTROGENIC COMPOUNDS FROM A PLANT AND USES THEREOF | UNIV SINGAPORE (SG) | 2005-02-23 | — | — | EP | disclosed |
| EP-1453827-A1 | METHODS FOR PREPARING AN ESTROGENIC PREPARATION AND ISOLATED ESTROGENIC COMPOUNDS FROM A PLANT AND USES THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-09-08 | — | — | EP | disclosed |
| US-6750248-B2 | FLAVONE ANALOGS MODULATE ESTROGEN RECEPTORS; USEFUL IN TREATING MENOPAUSE SYMPTOMS AND ESTROGEN-DEPENDENT CANCERS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-06-15 | — | — | US | disclosed |
| WO-2003040134-A9 | METHODS FOR PREPARING AN ESTROGENIC PREPARATION AND ISOLATED ESTROGENIC COMPOUNDS FROM A PLANT AND USES THEREOF | UNIV SINGAPORE (SG) | 2004-03-25 | — | — | WO | disclosed |
| US-20030190375-A1 | Therapeutical use of sophora flavescens or sophora subprostrata extracts | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 2003-10-09 | — | — | US | disclosed |
| US-20030180394-A1 | Extracts from sophora species, method for producing the same and their use | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 2003-09-25 | — | — | US | disclosed |
| US-20030170292-A1 | Methods for preparing an estrogenic preparation and isolated estrogenic compounds from a plant and uses thereof | NATIONAL UNIVERSITY OF SINGAPORE | 2003-09-11 | — | — | US | disclosed |
| WO-2003040134-A1 | METHODS FOR PREPARING AN ESTROGENIC PREPARATION AND ISOLATED ESTROGENIC COMPOUNDS FROM A PLANT AND USES THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2003-05-15 | — | — | WO | disclosed |
| WO-2002051426-A2 | COMPOSITIONS AND METHODS FOR TREATING SEXUAL DYSFUNCTION, ENHANCING SEXUAL FUNCTION, INCREASING TESTOSTERONE LEVELS, AND IMPROVING MUSCLE STRENGTH AND MASS | BRASWELL A GLENN (US) | 2002-07-04 | — | — | WO | disclosed |
| US-6071883-A | ADMINISTERING FLAVONE DERIVATIVE AS AN IMMUNOSUPPRESSANT TO THE RECIPIENT IN NEED OF A GRAFT REJECTION PREVENTION OR SUPPRESSION AFTER ALLOGRAFT ORGAN TRANSPLANT | CHEN HUIFANG (CA) | 2000-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030190375-A1 | Therapeutical use of sophora flavescens or sophora subprostrata extracts | SHBG, CYP19A1, HSD17B11 | VKORC1 226/4885IKBKB 1459/4885KMT2A 2820/4885 |
| US-20030170292-A1 | Methods for preparing an estrogenic preparation and isolated estrogenic compounds from a plant and uses thereof | ESR1, ESR2, GPER1 | VKORC1 539/4885IKBKB 1147/4885KMT2A 1431/4885 |
| US-20030180394-A1 | Extracts from sophora species, method for producing the same and their use | CYP19A1, SHBG, CYP17A1 | VKORC1 1360/4885IKBKB 791/4885KMT2A 3228/4885 |
| US-20230190852-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | PTGES, PTGES3, PTGES2 | VKORC1 269/4885IKBKB 174/4885KMT2A 3613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.