Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019378 | 0.90 | KMT2A (0.54) | KMT2AMEN1MAPTKDM4ERAB9A | |
| SCHEMBL29445396 | 0.80 | KMT2A (0.58) | KMT2AMEN1MAPTKDM4ERAB9A | |
| SCHEMBL41767 | 0.80 | KMT2A (0.58) | KMT2AMEN1MAPTKDM4ERAB9A | |
| SCHEMBL9019395 | 0.80 | RAB9A (0.57) | KMT2AMEN1MAPTKDM4ERAB9A | |
| SCHEMBL9019391 | 0.80 | RAB9A (0.57) | KMT2AMEN1MAPTKDM4ERAB9A | |
| SCHEMBL9019385 | 0.80 | RAB9A (0.57) | KMT2AMEN1MAPTKDM4ERAB9A | |
| SCHEMBL9019372 | 0.78 | KMT2A (0.56) | KMT2AMEN1MAPTKDM4ERAB9A | |
| SCHEMBL27008454 | 0.78 | ALDH1A1 (0.47) | KMT2AMEN1MAPTKDM4ERAB9A | |
| SCHEMBL28578766 | 0.77 | KMT2A (0.55) | KMT2AMEN1MAPTKDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL28638441 | 0.76 | KMT2A (0.53) | KMT2AMEN1MAPTKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0436348-B1 | Pyridyl cyclopropane derivatives with fungicidal activity | ZENECA LTD (GB) | 1996-11-13 | — | — | EP | disclosed |
| US-5126338-A | FUNGICIDES WHICH ARE N-PYRIDYL-CYCLOPROPANE CARBOXAMIDES OR DERIVATIVES THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-30 | — | — | US | disclosed |
| EP-0436348-A2 | Pyridyl cyclopropane derivatives with fungicidal activity | ZENECA LIMITED (GB) | 1991-07-10 | — | — | EP | disclosed |