Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.49 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PDE2A | O00408 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019690 | 0.90 | TBXA2R (0.56) | TBXA2RTBXAS1PTGDRMEN1ALDH1A1 | |
| SCHEMBL9019680 | 0.89 | TBXA2R (0.72) | TBXA2RTBXAS1PTGDRMEN1ALDH1A1 | |
| SCHEMBL9019710 | 0.89 | TBXA2R (0.57) | TBXA2RPTGDRMEN1ALDH1A1CYP3A4 | |
| SCHEMBL9019741 | 0.88 | TBXA2R (0.61) | TBXA2RTBXAS1PTGDRMEN1ALDH1A1 | |
| SCHEMBL9019718 | 0.87 | TBXA2R (0.69) | TBXA2RTBXAS1PTGDRMEN1ALDH1A1 | |
| SCHEMBL9019678 | 0.87 | TBXA2R (0.42) | TBXA2RTBXAS1MEN1ALDH1A1MAPT | |
| SCHEMBL9518093 | 0.85 | TBXA2R (0.77) | TBXA2RTBXAS1PTGDRPDE2A | |
| SCHEMBL9518380 | 0.85 | TBXA2R (0.67) | TBXA2RTBXAS1PTGDRMEN1ALDH1A1 | |
| SCHEMBL9518277 | 0.84 | TBXA2R (0.64) | TBXA2RTBXAS1PTGDRMEN1ALDH1A1 | |
| SCHEMBL10413596 | 0.84 | TBXA2R (0.74) | TBXA2RTBXAS1PTGDRPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | claimed |
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | disclosed |
| US-5238953-A | Thromboxane a2 antagonist | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-08-24 | — | — | US | disclosed |
| EP-0496237-A2 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA S.p.A. (IT) | 1992-07-29 | — | — | EP | disclosed |