Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 9/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019683 | 0.89 | TBXA2R (0.51) | TBXA2RTBXAS1HDAC1HDAC6HDAC3 | |
| SCHEMBL9019727 | 0.89 | TBXA2R (0.43) | TBXA2RKDM4EMAPTMEN1MITF | |
| SCHEMBL9019685 | 0.87 | TBXA2R (0.57) | TBXA2RTBXAS1MAPTMEN1ALDH1A1 | |
| SCHEMBL9019676 | 0.84 | TBXA2R (0.47) | TBXA2RTBXAS1HDAC1HDAC6HDAC3 | |
| SCHEMBL9019726 | 0.81 | TBXA2R (0.52) | TBXA2RTBXAS1PTGDR2 | |
| SCHEMBL9019713 | 0.80 | TBXA2R (0.53) | TBXA2RTBXAS1HDAC1HDAC6HDAC3 | |
| SCHEMBL9019690 | 0.79 | TBXA2R (0.56) | TBXA2RTBXAS1MAPTMEN1ALDH1A1 | |
| SCHEMBL9019682 | 0.78 | TBXA2R (0.52) | TBXA2RMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL9019710 | 0.77 | TBXA2R (0.57) | TBXA2RMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL9019680 | 0.77 | TBXA2R (0.72) | TBXA2RTBXAS1MAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | claimed |
| EP-0496237-A2 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA S.p.A. (IT) | 1992-07-29 | — | — | EP | claimed |
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | disclosed |
| US-5238953-A | Thromboxane a2 antagonist | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-08-24 | — | — | US | disclosed |
| EP-0496237-A2 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA S.p.A. (IT) | 1992-07-29 | — | — | EP | disclosed |