Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | SYNJ2 | O15056 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30775720 | 1.00 | CYP3A4 (0.48) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL30775787 | 1.00 | CYP3A4 (0.48) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL29355417 | 1.00 | CYP3A4 (0.48) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL460037 | 1.00 | CYP3A4 (0.48) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL1659938 | 1.00 | CYP3A4 (0.48) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL30775723 | 1.00 | CYP3A4 (0.48) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL18746282 | 1.00 | CYP3A4 (0.48) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL460038 | 1.00 | CYP3A4 (0.48) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL1659934 | 1.00 | CYP3A4 (0.48) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL1660720 | 1.00 | CYP3A4 (0.48) | CYP3A4KDM4EHSD17B10MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8259555-A | — | — | None | — | — | JP | disclosed |
| US-20200179477-A1 | DIETARY SUPPLEMENT DERIVED FROM NATURAL PRODUCTS BY HOT MELT EXTRUSION (HME) PROCESSING | ESTRADA RAMIREZ OMAR AUGUSTO (CO) | 2020-06-11 | — | — | US | disclosed |
| US-20120208118-A1 | RESIN COMPOSITIONS AND PROCESSES | XEROX CORPORATION (US) | 2012-08-16 | — | — | US | disclosed |
| US-20120208118-A1 | RESIN COMPOSITIONS AND PROCESSES | XEROX CORPORATION (US) | 2012-08-16 | — | — | US | disclosed |
| JP-H08259555-A | OPTICALLY ACTIVE TRANS-3-HYDROXYFLAVAN DERIVATIVE AND ITS PRODUCTION | KAWAKEN FINE CHEM CO LTD | 1996-10-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200179477-A1 | DIETARY SUPPLEMENT DERIVED FROM NATURAL PRODUCTS BY HOT MELT EXTRUSION (HME) PROCESSING | LIPA, CEL, FABP2 | CYP3A4 2318/4885KDM4E 1747/4885HSD17B10 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.