Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD3 | Q15059 | 12/20 | 0.55 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019672 | 0.83 | BRD3 (0.60) | BRD3MAPKAPK2S1PR1 | |
| SCHEMBL4105569 | 0.80 | KMT2A (0.52) | BRD3MAPKAPK2S1PR1HTR2AHTR2C | |
| SCHEMBL13376384 | 0.76 | KMT2A (0.52) | BRD3S1PR1CDKN1ASIRT1 | |
| SCHEMBL30762338 | 0.76 | S1PR1 (0.59) | BRD3MAPKAPK2S1PR1 | |
| SCHEMBL5421567 | 0.76 | S1PR1 (0.59) | BRD3MAPKAPK2S1PR1 | |
| SCHEMBL5088953 | 0.76 | S1PR1 (0.59) | BRD3MAPKAPK2S1PR1 | |
| SCHEMBL29141416 | 0.76 | S1PR1 (0.59) | BRD3MAPKAPK2S1PR1 | |
| SCHEMBL6692540 | 0.76 | S1PR1 (0.48) | BRD3MAPKAPK2S1PR1HTR2AHTR2C | |
| SCHEMBL9658727 | 0.74 | SIRT1 (0.56) | MAPKAPK2S1PR1HTR2AHTR2CCDKN1A | |
| SCHEMBL16266024 | 0.73 | MAPT (0.77) | BRD3SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | disclosed |
| US-5238953-A | Thromboxane a2 antagonist | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-08-24 | — | — | US | disclosed |
| EP-0496237-A2 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA S.p.A. (IT) | 1992-07-29 | — | — | EP | disclosed |