Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 11/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 8/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019683 | 0.91 | TBXA2R (0.51) | TBXA2RTBXAS1PTGDR2 | |
| SCHEMBL9019712 | 0.89 | TBXA2R (0.53) | TBXA2RTBXAS1PTGDR2FABP3 | |
| SCHEMBL9019676 | 0.86 | TBXA2R (0.47) | TBXA2RTBXAS1PTGDR2 | |
| SCHEMBL9019689 | 0.86 | TBXA2R (0.71) | TBXA2RTBXAS1 | |
| SCHEMBL9019713 | 0.85 | TBXA2R (0.53) | TBXA2RTBXAS1PTGDR2 | |
| SCHEMBL9019678 | 0.81 | TBXA2R (0.42) | TBXA2RTBXAS1PTGDR2 | |
| SCHEMBL9019686 | 0.80 | TBXA2R (0.48) | TBXA2RTBXAS1PTGDR2 | |
| SCHEMBL9019682 | 0.80 | TBXA2R (0.52) | TBXA2RPTGDR2 | |
| SCHEMBL10412691 | 0.79 | TBXA2R (0.70) | TBXA2RTBXAS1PTGDR2 | |
| SCHEMBL9019680 | 0.77 | TBXA2R (0.72) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | claimed |
| EP-0496237-A2 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA S.p.A. (IT) | 1992-07-29 | — | — | EP | claimed |
| EP-0496237-B1 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA SPA (IT) | 1996-02-14 | — | — | EP | disclosed |
| US-5238953-A | Thromboxane a2 antagonist | FARMITALIA CARLO ERBA S.R.L. (IT) | 1993-08-24 | — | — | US | disclosed |
| EP-0496237-A2 | N-imidazolyl derivatives of substituted tetrahydrocarbazole and cyclohept[b]indole | PHARMACIA S.p.A. (IT) | 1992-07-29 | — | — | EP | disclosed |