Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463412 | 0.91 | ALDH1A1 (0.53) | ALDH1A1TSHRLPAR1LPAR3LPAR2 | |
| SCHEMBL9463771 | 0.85 | NAAA (0.46) | ALDH1A1HSD17B10TDP1LPAR1LPAR3 | |
| SCHEMBL10105551 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HSD17B10TSHRTDP1LPAR1 | |
| SCHEMBL9019745 | 0.85 | ALDH1A1 (0.47) | ALDH1A1HSD17B10TSHRTDP1LPAR1 | |
| SCHEMBL11258229 | 0.84 | ALDH1A1 (0.37) | ALDH1A1HSD17B10TSHRTDP1LMNA | |
| SCHEMBL10683643 | 0.80 | USP2 (0.50) | LPAR1LPAR3LPAR2PLA2G2CUSP2 | |
| SCHEMBL9019825 | 0.80 | ALDH1A1 (0.37) | ALDH1A1HSD17B10TSHRTDP1LMNA | |
| SCHEMBL3392461 | 0.80 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TSHRTDP1LMNA | |
| SCHEMBL2466001 | 0.80 | TDP1 (0.42) | ALDH1A1HSD17B10TSHRTDP1LMNA | |
| SCHEMBL9575535 | 0.80 | HSD17B10 (0.48) | HSD17B10TDP1LPAR1LPAR3LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-B1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0448006-B1 | Process for the preparation of acylales | HOECHST AG (DE) | 1995-01-25 | — | — | EP | disclosed |
| US-5231221-A | PROCESS FOR THE PREPARATION OF ACYLALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-27 | — | — | US | disclosed |
| US-5225590-A | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1993-07-06 | — | — | US | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |
| EP-0448006-A2 | Process for the preparation of acylales | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-09-25 | — | — | EP | disclosed |
| EP-0187297-B1 | ALKOXY METHYL ETHER AND ALKOXY METHYL ESTER DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1991-08-21 | — | — | EP | disclosed |
| EP-0187297-A2 | Alkoxy methyl ether and alkoxy methyl ester derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-07-16 | — | — | EP | disclosed |