Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019822 | 0.77 | MEN1 (0.48) | MEN1ALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL7454607 | 0.76 | GDA (0.54) | GDAMEN1ALDH1A1BLMKMT2A | |
| SCHEMBL11471010 | 0.76 | GDA (0.57) | GDAALDH1A1LMNASMN1; SMN2PDE4A | |
| SCHEMBL9019840 | 0.74 | HPGD (0.46) | GDAMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9194843 | 0.73 | GDA (0.62) | GDAMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL25286007 | 0.71 | GDA (0.55) | GDAMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL1460591 | 0.71 | GDA (0.63) | GDAMEN1ALDH1A1KMT2APDE4A | |
| SCHEMBL7453665 | 0.70 | GDA (0.58) | GDAMEN1ALDH1A1KMT2APDE4A | |
| SCHEMBL9197448 | 0.70 | GDA (0.57) | GDAMEN1ALDH1A1LMNACYP3A4 | |
| SCHEMBL9161807 | 0.70 | GDA (0.57) | GDAALDH1A1SMN1; SMN2PDE4AADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-B1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |