Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467775 | 0.90 | KMT2A (0.50) | HPGDKMT2AMEN1TSHRGDA | |
| SCHEMBL9019822 | 0.81 | MEN1 (0.48) | HPGDKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL9019742 | 0.79 | ACHE (0.33) | KMT2AMEN1ALDH1A1SMN1; SMN2PDE3A | |
| SCHEMBL9021299 | 0.78 | ACHE (0.42) | HPGD | |
| SCHEMBL9538971 | 0.78 | HPGD (0.43) | HPGDKMT2AMEN1TSHRGDA | |
| SCHEMBL9540513 | 0.78 | HPGD (0.45) | HPGDKMT2AMEN1TSHRGDA | |
| SCHEMBL9540520 | 0.78 | HPGD (0.45) | HPGDKMT2AMEN1TSHRGDA | |
| SCHEMBL9538872 | 0.78 | HPGD (0.43) | HPGDKMT2AMEN1TSHRGDA | |
| SCHEMBL9538968 | 0.78 | HPGD (0.43) | HPGDKMT2AMEN1TSHRGDA | |
| SCHEMBL9540499 | 0.78 | HPGD (0.45) | HPGDKMT2AMEN1TSHRGDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452680-B1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AG (DE) | 1996-11-06 | — | — | EP | disclosed |
| EP-0452680-A1 | Substituted purines, process for their preparation and their use as antiviral agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-23 | — | — | EP | disclosed |