⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805896 | 0.83 | CA1 (0.37) | — | |
| SCHEMBL3014271 | 0.82 | CA2 (0.36) | — | |
| SCHEMBL22044521 | 0.78 | CA1 (0.44) | — | |
| SCHEMBL26292947 | 0.77 | CA1 (0.32) | — | |
| SCHEMBL901982 | 0.76 | — | — | |
| SCHEMBL17033956 | 0.74 | — | — | |
| SCHEMBL10962640 | 0.74 | CA12 (0.53) | — | |
| SCHEMBL3420782 | 0.72 | — | — | |
| SCHEMBL18609546 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL3094775 | 0.72 | ANPEP (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011107283-A2 | FORMULATIONS OF TAUROLIDINE AND METHOD FOR THE PRODUCTION THEREOF | GAMPTEC GMBH (DE) | 2011-09-09 | — | — | WO | claimed |
| US-5077281-A | Anticoagulants | BIOLINK CORPORATION | 1991-12-31 | — | — | US | claimed |
| EP-2621458-B1 | ANTIMICROBIAL DENTAL CARE PREPARATION | GEISTLICH PHARMA AG (CH) | 2017-04-19 | — | — | EP | disclosed |
| EP-1595543-B1 | Antineoplastic pharmaceutical compositions comprising taurolidine or taurultam and 5-fluorouracil | ED GEISTLICH SÖHNE AG FÜR CHEMISCHE IND (CH) | 2014-12-17 | — | — | EP | disclosed |
| US-8852617-B2 | Antimicrobial dental care preparation | GEISTLICH PHARMA AG (CH) | 2014-10-07 | — | — | US | disclosed |
| EP-2621458-A1 | ANTIMICROBIAL DENTAL CARE PREPARATION | Geistlich Pharma AG (CH) | 2013-08-07 | — | — | EP | disclosed |
| US-20130189199-A1 | ANTIMICROBIAL DENTAL CARE PREPARATION | GEISTLICH PHARMA AG (CH) | 2013-07-25 | — | — | US | disclosed |
| US-8394397-B2 | mixture of methylol transfer agents such as taurolidine or taurultam and biodegradative adhesive for adhesion to tissues | ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE (CH) | 2013-03-12 | — | — | US | disclosed |
| US-8236794-B2 | Antitumor agents; using taurolidine; administering into lungs | ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE (CH) | 2012-08-07 | — | — | US | disclosed |
| US-8202860-B2 | Methods and compositions for treating primary and secondary tumors of the central nervous system (CNS) | ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE (CH) | 2012-06-19 | — | — | US | disclosed |
| WO-2012042349-A1 | ANTIMICROBIAL DENTAL CARE PREPARATION | GEISTLICH PHARMA AG (CH) | 2012-04-05 | — | — | WO | disclosed |
| EP-1462125-A2 | Adhesive antineoplastic compositions | ED. GEISTLICH SÖHNE AG FÜR CHEMISCHE INDUSTRIE (CH) | 2004-09-29 | — | — | EP | disclosed |
| US-20030225067-A1 | Microdialysis methods and applications for treatment and/or prophylaxis of tumors and/or infections in the central nervous system (CNS) and/or in other parenchymal organs | ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE (CH) | 2003-12-04 | — | — | US | disclosed |
| US-20030195198-A1 | Methods and compositions for treating primary and secondary tumors of the central nervous system (CNS) | STENDEL RUEDIGER (DE) | 2003-10-16 | — | — | US | disclosed |
| EP-1346745-A1 | Apparatus for treatment of tumor in the central nervous system (CNS) | ED. GEISTLICH SÖHNE AG FÜR CHEMISCHE INDUSTRIE (CH) | 2003-09-24 | — | — | EP | disclosed |
| US-20030064942-A1 | Methods and compositions for treating primary and secondary tumors of the central nervous system (CNS) | STENDEL RUEDIGER (DE) | 2003-04-03 | — | — | US | disclosed |
| US-6479481-B1 | ADMINISTERING AN EFFECTIVE DOSE OF A CNS TUMOR-INHIBITING METHYLOL TRANSFER AGENT SUCH AS: TAUROLIDINE, TAURULTAM OR A MIXTURE THEREOF. | ED. GEISTLICH SOEHNE AG FUR CHEMISCHE INDUSTRIE (CH) | 2002-11-12 | — | — | US | disclosed |
| EP-1103251-A1 | Use of 1,1-dioxoperhydro-1,2,4-thiadiazines | Goldschmidt AG (DE) | 2001-05-30 | — | — | EP | disclosed |
| EP-1066830-A2 | Uses and compositions for treating primary and secondary tumors of the central nervous system (cns) | ED. GEISTLICH SÖHNE AG FÜR CHEMISCHE INDUSTRIE (CH) | 2001-01-10 | — | — | EP | disclosed |
| US-5077281-A | Anticoagulants | BIOLINK CORPORATION | 1991-12-31 | — | — | US | disclosed |