Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 16/20 | 0.62 |
| ▸ | PGR | P06401 | 15/20 | 0.62 |
| ▸ | AR | P10275 | 13/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | SHBG | P04278 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019827 | 0.91 | NR3C1 (0.59) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019799 | 0.88 | NR3C1 (0.63) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL19042656 | 0.87 | NR3C1 (0.68) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL21729781 | 0.87 | NR3C1 (0.68) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL8407056 | 0.87 | NR3C1 (0.48) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019806 | 0.86 | NR3C1 (0.61) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019798 | 0.85 | NR3C1 (0.67) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019846 | 0.85 | NR3C1 (0.83) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019810 | 0.85 | PGR (0.65) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019833 | 0.84 | PGR (0.64) | NR3C1PGRARCYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404283-B1 | 11-Beta-aryl-4-estrene, method for its production and its use as a medicine | SCHERING AG (DE) | 1996-05-08 | — | — | EP | claimed |