Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 11/20 | 0.44 |
| ▸ | AR | P10275 | 10/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019864 | 0.85 | ALDH1A1 (0.50) | SERPINA6ALDH1A1SLC22A1SHBGTHRB | |
| SCHEMBL8536771 | 0.85 | SERPINA6 (0.58) | SERPINA6ALDH1A1SLC22A1SHBGTHRB | |
| SCHEMBL19042741 | 0.85 | SERPINA6 (0.58) | SERPINA6ALDH1A1SLC22A1SHBGTHRB | |
| SCHEMBL8536980 | 0.85 | SERPINA6 (0.52) | SERPINA6ALDH1A1SLC22A1SHBGTHRB | |
| SCHEMBL9019849 | 0.85 | SERPINA6 (0.52) | SERPINA6ALDH1A1SLC22A1SHBGTHRB | |
| SCHEMBL9019886 | 0.85 | SERPINA6 (0.52) | SERPINA6ALDH1A1SLC22A1SHBGTHRB | |
| SCHEMBL20048229 | 0.84 | SERPINA6 (0.57) | SERPINA6ALDH1A1SLC22A1SHBGTHRB | |
| SCHEMBL8540722 | 0.82 | ALDH1A1 (0.49) | SERPINA6ALDH1A1SLC22A1SHBGTHRB | |
| SCHEMBL23131144 | 0.82 | SERPINA6 (0.55) | SERPINA6ALDH1A1SLC22A1SHBGTHRB | |
| SCHEMBL19042720 | 0.82 | PGR (0.60) | SERPINA6ALDH1A1SLC22A1SHBGTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404283-B1 | 11-Beta-aryl-4-estrene, method for its production and its use as a medicine | SCHERING AG (DE) | 1996-05-08 | — | — | EP | disclosed |
| EP-0404283-A2 | 11-Beta-aryl-4-estrene, method for its production and its use as a medicine | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-12-27 | — | — | EP | disclosed |