Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPD | P32754 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492645 | 0.84 | ALDH1A1 (0.58) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL8492650 | 0.84 | ALDH1A1 (0.58) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL8493162 | 0.80 | HPD (0.57) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL997302 | 0.79 | ALDH1A1 (0.59) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL31492417 | 0.78 | ALDH1A1 (0.52) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL6072863 | 0.77 | HPD (0.50) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL3410406 | 0.77 | ALDH1A1 (0.46) | MAPTALDH1A1KMT2APKMLMNA | |
| SCHEMBL6487862 | 0.76 | ALDH1A1 (0.55) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL6487852 | 0.76 | ALDH1A1 (0.55) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL3016186 | 0.75 | ALDH1A1 (0.47) | MAPTALDH1A1PKMCYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |