Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | EDNRB | P24530 | 2/20 | 0.36 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019961 | 0.84 | EDNRB (0.42) | ALDH1A1KDM4ECYP1A2EDNRBEDNRA | |
| SCHEMBL8975749 | 0.78 | ALDH1A1 (0.42) | ALDH1A1POLBKDM4EMAPTCYP1A2 | |
| SCHEMBL8873130 | 0.77 | ALDH1A1 (0.41) | ALDH1A1POLBKDM4EMAPTCYP1A2 | |
| SCHEMBL9902864 | 0.75 | SMN1; SMN2 (0.48) | ALDH1A1POLBKDM4EMAPTCYP1A2 | |
| SCHEMBL9774228 | 0.75 | CYP1A2 (0.37) | ALDH1A1POLBKDM4EMAPTCYP1A2 | |
| SCHEMBL16751946 | 0.74 | KCNB1 (0.41) | ALDH1A1POLBSMN1; SMN2TSHRMAPK1 | |
| SCHEMBL9774221 | 0.74 | POLB (0.36) | ALDH1A1POLBKDM4EMAPTCYP1A2 | |
| SCHEMBL9878688 | 0.72 | EDNRB (0.44) | ALDH1A1POLBCYP1A2SMN1; SMN2EDNRB | |
| SCHEMBL9701288 | 0.71 | POLB (0.39) | ALDH1A1POLBKDM4EMAPTCYP1A2 | |
| SCHEMBL577793 | 0.70 | ALDH1A1 (0.52) | ALDH1A1POLBKDM4EMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422751-B1 | Substituted 2-pyrimidinyl and 2-triazinylacetic acid derivatives, process for their preparation and their use as agent with herbicidal, fungicidal and plant growth regulating activity | HOECHST SCHERING AGREVO GMBH (DE) | 1996-08-14 | — | — | EP | disclosed |
| US-5238907-A | Substituted 2-pyrimidinyl-acetic acid derivatives, and their use as herbicides, fungicides and plant growth regulators | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-08-24 | — | — | US | disclosed |
| US-5098465-A | Triazine or pyrimidine acetic acids or amides | SHERING AKTIENGESELLSCHAFT (DE) | 1992-03-24 | — | — | US | disclosed |
| EP-0422751-A2 | Substituted 2-pyrimidinyl and 2-triazinylacetic acid derivatives, process for their preparation and their use as agent with herbicidal, fungicidal and plant growth regulating activity | Hoechst Schering AgrEvo GmbH (DE) | 1991-04-17 | — | — | EP | disclosed |