Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366165 | 0.77 | DPP4 (0.34) | KDM1AKCNH2KDM1B | |
| SCHEMBL150028 | 0.76 | DPP4 (0.41) | — | |
| SCHEMBL13068536 | 0.75 | KDM1A (0.36) | KDM1AKCNH2KDM1B | |
| SCHEMBL902187 | 0.75 | KDM1A (0.36) | KDM1AKCNH2KDM1B | |
| SCHEMBL903950 | 0.75 | GABRA1 (0.37) | KDM1AKCNH2KDM1B | |
| SCHEMBL707949 | 0.75 | KDM1A (0.32) | KDM1AKCNH2KDM1B | |
| SCHEMBL29387214 | 0.75 | KDM1A (0.32) | KDM1AKCNH2KDM1B | |
| SCHEMBL28455267 | 0.75 | KDM1A (0.32) | KDM1AKCNH2KDM1B | |
| SCHEMBL28455266 | 0.73 | KDM1A (0.31) | KDM1AKCNH2KDM1B | |
| SCHEMBL23748185 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621919-A1 | PHENYLQUINAZOLINE DERIVATIVES | Merck Patent GmbH (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041435-A1 | PHENYLQUINAZOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-04-05 | — | — | WO | disclosed |