Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18805568 | 0.84 | GABRA1 (0.33) | GABRA1GABRB2KDM1AKDM1BALOX15 | |
| SCHEMBL14292894 | 0.83 | KDM1A (0.39) | GABRA1GABRB2DPP4KDM1AKCNH2 | |
| SCHEMBL14659123 | 0.82 | ALOX15 (0.42) | ALOX15ALOX12 | |
| SCHEMBL16077254 | 0.82 | GABRA1 (0.32) | GABRA1GABRB2 | |
| SCHEMBL21358356 | 0.82 | CA1 (0.34) | GABRA1GABRB2ALOX15 | |
| SCHEMBL11807767 | 0.81 | GABRA1 (0.46) | GABRA1GABRB2ALOX15ALOX12SMN1; SMN2 | |
| SCHEMBL15132117 | 0.81 | GRIN2D (0.42) | GABRA1GABRB2DPP4ALOX15ALOX12 | |
| SCHEMBL25619918 | 0.81 | NPC1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL10099963 | 0.81 | TAAR1 (0.32) | GABRA1GABRB2 | |
| SCHEMBL20575666 | 0.79 | LMNA (0.41) | GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041435-A1 | PHENYLQUINAZOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2012-04-05 | — | — | WO | disclosed |