Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823777 | 0.69 | MAPK1 (0.51) | GSK3AGSK3BPIN1PIN4ALDH1A1 | |
| SCHEMBL7206290 | 0.68 | MAPK1 (0.49) | GSK3AGSK3BPIN1PIN4ALDH1A1 | |
| SCHEMBL2828076 | 0.67 | GAA (0.49) | GSK3AGSK3BPIN1PIN4ALDH1A1 | |
| SCHEMBL27746407 | 0.67 | NLRP3 (0.50) | GSK3AGSK3BPIN1PIN4ALDH1A1 | |
| SCHEMBL5660336 | 0.67 | NOTUM (0.61) | ALDH1A1MEN1KMT2AALOX15SMN1; SMN2 | |
| SCHEMBL16424936 | 0.66 | TSHR (0.49) | GSK3AGSK3BPIN1PIN4ALDH1A1 | |
| SCHEMBL31518536 | 0.66 | SMN1; SMN2 (0.49) | GSK3AGSK3BALDH1A1MEN1KMT2A | |
| SCHEMBL315410 | 0.66 | HSD17B10 (0.49) | GSK3AGSK3BPIN1PIN4ALDH1A1 | |
| SCHEMBL24127303 | 0.65 | DRD2 (0.33) | — | |
| SCHEMBL9708708 | 0.65 | GSK3A (0.49) | GSK3AGSK3BPIN1PIN4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332156-B1 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-12-18 | — | — | EP | disclosed |
| US-5366970-A | Cephem compounds and pharmaceutically acceptable salts thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-22 | — | — | US | disclosed |
| US-5173485-A | Bactericides, microbiocides | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-12-22 | — | — | US | disclosed |
| EP-0332156-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0327492-A1 | Herbicidally and plantgrowth regulatory active quinoline and pyrindine compounds | CIBA-GEIGY AG (CH) | 1989-08-09 | — | — | EP | disclosed |