Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020345 | 0.87 | ABCB1 (0.34) | ABCB1 | |
| SCHEMBL8112409 | 0.84 | ABCB1 (0.34) | ABCB1 | |
| SCHEMBL8108361 | 0.84 | ABCB1 (0.34) | ABCB1 | |
| SCHEMBL9595521 | 0.84 | ABCB1 (0.34) | ABCB1 | |
| SCHEMBL8106554 | 0.79 | ABCB1 (0.35) | ABCB1 | |
| SCHEMBL9595418 | 0.79 | ABCB1 (0.35) | ABCB1 | |
| SCHEMBL8106596 | 0.79 | ABCB1 (0.34) | ABCB1 | |
| SCHEMBL12431668 | 0.79 | NR1H2 (0.37) | ABCB1 | |
| SCHEMBL9519428 | 0.77 | SRC (0.34) | ABCB1 | |
| SCHEMBL2080032 | 0.77 | SRC (0.35) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449191-B1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5438054-A | Antibacterial agent | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |
| WO-1991014687-A1 | 2-(SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-03 | — | — | WO | disclosed |
| EP-0449191-A1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |