Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 3/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20819522 | 0.80 | XDH (0.38) | PNPGDAKDM4EALDH1A1LMNA | |
| SCHEMBL14260671 | 0.79 | GDA (0.39) | PNPGDAKDM4EALDH1A1LMNA | |
| SCHEMBL28969 | 0.79 | PDPK1 (0.41) | TYMSPNPGDAKDM4EALDH1A1 | |
| SCHEMBL1901598 | 0.75 | GDA (0.60) | PNPGDAXDH | |
| SCHEMBL5062459 | 0.75 | XDH (0.46) | PNPGDAKDM4EALDH1A1XDH | |
| SCHEMBL27496340 | 0.75 | GDA (0.36) | PNPGDAKDM4EALDH1A1LMNA | |
| SCHEMBL10047094 | 0.75 | XDH (0.40) | PNPGDAKDM4EALDH1A1LMNA | |
| SCHEMBL5021600 | 0.75 | PIM1 (0.38) | PNPGDAKDM4EALDH1A1XDH | |
| SCHEMBL732552 | 0.75 | KDM4E (0.51) | PNPGDAKDM4EALDH1A1LMNA | |
| Lithium SCHEMBL30870625 | 0.74 | GDA (0.58) | PNPGDAXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717744-A1 | A PROCESS FOR THE PREPARATION OF 9-(2-HYDROXY)-ETHOXYMETHYL-GUANINE | RECORDATI CHEM PHARM (CH) | 1996-06-26 | — | — | EP | claimed |
| WO-1995007281-A1 | A PROCESS FOR THE PREPARATION OF 9-(2-HYDROXY)-ETHOXYMETHYL-GUANINE | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1995-03-16 | — | — | WO | claimed |
| EP-0717744-A1 | A PROCESS FOR THE PREPARATION OF 9-(2-HYDROXY)-ETHOXYMETHYL-GUANINE | RECORDATI CHEM PHARM (CH) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007281-A1 | A PROCESS FOR THE PREPARATION OF 9-(2-HYDROXY)-ETHOXYMETHYL-GUANINE | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1995-03-16 | — | — | WO | disclosed |
| WO-1995007281-A1 | A PROCESS FOR THE PREPARATION OF 9-(2-HYDROXY)-ETHOXYMETHYL-GUANINE | RECORDATI S.A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1995-03-16 | — | — | WO | disclosed |