SCHEMBL28969

SCHEMBL28969

CNc1nc2[nH]cnc2c(=O)[nH]1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 3/20 0.41
GDA Q9Y2T3 2/20 0.39
PNP P00491 1/20 0.39
TYMS P04818 1/20 0.37
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
CSNK2A1 P68400 1/20 0.37
XDH P47989 4/20 0.36
ACHE P22303 1/20 0.34
PARP1 P09874 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
GLA P06280 1/20 0.34
PMP22 Q01453 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10379702 0.86 GDA (0.34) PDPK1GDAPNPTYMSKDM4E
SCHEMBL14260671 0.82 GDA (0.39) GDAPNPXDHACHEKDM4E
SCHEMBL27496340 0.81 GDA (0.36) PDPK1GDAPNPXDHPARP1
SCHEMBL10047094 0.81 XDH (0.40) PDPK1GDAPNPXDHACHE
SCHEMBL5062459 0.81 XDH (0.46) GDAPNPXDHKDM4EALDH1A1
SCHEMBL5021600 0.81 PIM1 (0.38) PDPK1GDAPNPXDHPARP1
SCHEMBL219477 0.80 GDA (0.62) GDAPNPKDM4EALDH1A1LMNA
SCHEMBL9020532 0.79 TYMS (0.39) PDPK1GDAPNPTYMSXDH
SCHEMBL26174316 0.79 XDH (0.53) GDAPNPXDHKDM4EALDH1A1
SCHEMBL17373199 0.79 CSNK2A2 (0.37) PDPK1CSNK2A2CSNK2BCSNK2A1XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2828 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
WO-2026088246-A1 METHOD FOR PRODUCING LOW-MOLECULAR-WEIGHT COMPOUND NTT株式会社 2026-04-30 WO claimed
WO-2025111452-A2 CHEMICAL MODIFICATIONS IN PEgRNA and ngRNAs PRIME MEDICINE, INC. (US) 2025-05-30 WO claimed
WO-2025111430-A1 CHEMICAL MODIFICATIONS IN mRNA POLY(A) TAIL PRIME MEDICINE, INC. (US) 2025-05-30 WO claimed
WO-2025043082-A2 COMPOSITIONS AND METHODS TO IMPROVE RNA PROPERTIES USING BASE, PHOSPHODIESTER LINKAGE, SUGAR BACKBONE, AND CAP MODIFICATIONS THE BROAD INSTITUTE, INC. (US) 2025-02-27 WO claimed
WO-2025038970-A1 MODIFIED OLIGONUCLEOTIDES CONTAINING MULTIPLE OLIGONUCLEOTIDES ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 WO claimed
WO-2025038963-A1 OLIGONUCLEOTIDES CONTAINING MULTIPLE LIGANDS AND/OR LIPIDS ADARX PHARMACEUTICALS, INC. (US) 2025-02-20 WO claimed
US-8188254-B2 C-class oligonucleotide analogs with enhanced immunostimulatory potency COLEY PHARMACEUTICAL GMBH (DE) 2012-05-29 US claimed
CN-101454451-A Class C oligonucleotide analogs with enhanced immunostimulatory capacity COLEY PHARM GMBH (DE) 2009-06-10 CN claimed
EP-1728863-A2 C-class oligonucleotide analogs with enhanced immunostimulatory potency Coley Pharmaceutical GmbH (DE) 2006-12-06 EP claimed
EP-1678303-A2 C-CLASS OLIGONUCLEOTIDE ANALOGS WITH ENHANCED IMMUNOSTIMULATORY POTENCY Coley Pharmaceutical GmbH (DE) 2006-07-12 EP claimed
US-20050239734-A1 C-class oligonucleotide analogs with enhanced immunostimulatory potency COLEY PHARMACEUTICAL GMBH (DE) 2005-10-27 US claimed
EP-1578954-A2 5' CPG NUCLEIC ACIDS AND METHODS OF USE Coley Pharmaceutical Group, Inc. (US) 2005-09-28 EP claimed
WO-2005042018-A2 C-CLASS OLIGONUCLEOTIDE ANALOGS WITH ENHANCED IMMUNOSTIMULATORY POTENCY COLEY PHARMACEUTICAL GMBH (DE) 2005-05-12 WO claimed
US-20040171571-A1 5' CpG nucleic acids and methods of use COLEY PHARMACEUTICAL GROUP, INC. (US) 2004-09-02 US claimed
WO-2004053104-A2 5’ CPG NUCLEIC ACIDS AND METHODS OF USE COLEY PHARMACEUTICAL GROUP, INC. (US) 2004-06-24 WO claimed
EP-0775142-A1 SUBSTITUTED O6 -BENZYLGUANINES AND 6(4)-BENZYLOXYPYRIMIDINES THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) 1997-05-28 EP claimed