Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.31 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020538 | 1.00 | CHRM1 (0.34) | CHRM1AGTR2CYP19A1LMNAMAPK1 | |
| SCHEMBL9020448 | 0.93 | CHRM1 (0.33) | CHRM1CYP19A1LMNAMAPK1RAB9A | |
| SCHEMBL9020455 | 0.93 | CHRM1 (0.33) | CHRM1CYP19A1LMNAMAPK1RAB9A | |
| SCHEMBL9020689 | 0.91 | CYP19A1 (0.34) | CHRM1CYP19A1LMNAMAPK1RAB9A | |
| SCHEMBL9020693 | 0.91 | CYP19A1 (0.34) | CHRM1CYP19A1LMNAMAPK1RAB9A | |
| SCHEMBL9020118 | 0.91 | CYP19A1 (0.33) | CHRM1CYP19A1LMNAMAPK1RAB9A | |
| SCHEMBL9020110 | 0.91 | CYP19A1 (0.33) | CHRM1CYP19A1LMNAMAPK1RAB9A | |
| SCHEMBL9020459 | 0.90 | CHRM1 (0.34) | CHRM1CYP19A1LMNAMAPK1RAB9A | |
| SCHEMBL9020462 | 0.90 | CHRM1 (0.34) | CHRM1CYP19A1LMNAMAPK1RAB9A | |
| SCHEMBL9020606 | 0.85 | RAB9A (0.38) | CHRM1LMNAMAPK1RAB9AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449191-B1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5438054-A | Antibacterial agent | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |
| WO-1991014687-A1 | 2-(SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-03 | — | — | WO | disclosed |
| EP-0449191-A1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |