Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.31 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | TGM2 | P21980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020693 | 1.00 | CYP19A1 (0.34) | CYP19A1CHRM1POLBFAAHPLA2G4A | |
| SCHEMBL9020540 | 0.91 | CHRM1 (0.34) | CYP19A1CHRM1FAAHPLA2G4APLA2G6 | |
| SCHEMBL9020538 | 0.91 | CHRM1 (0.34) | CYP19A1CHRM1FAAHPLA2G4APLA2G6 | |
| SCHEMBL9020455 | 0.89 | CHRM1 (0.33) | CYP19A1CHRM1FAAHPLA2G4APLA2G6 | |
| SCHEMBL9020448 | 0.89 | CHRM1 (0.33) | CYP19A1CHRM1FAAHPLA2G4APLA2G6 | |
| SCHEMBL9020118 | 0.88 | CYP19A1 (0.33) | CYP19A1CHRM1FAAHLMNAMAPK1 | |
| SCHEMBL9020110 | 0.88 | CYP19A1 (0.33) | CYP19A1CHRM1FAAHLMNAMAPK1 | |
| SCHEMBL9020462 | 0.86 | CHRM1 (0.34) | CYP19A1CHRM1FAAHPLA2G4APLA2G6 | |
| SCHEMBL9020459 | 0.86 | CHRM1 (0.34) | CYP19A1CHRM1FAAHPLA2G4APLA2G6 | |
| SCHEMBL9020606 | 0.81 | RAB9A (0.38) | CHRM1FAAHSIGMAR1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449191-B1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | BANYU PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5438054-A | Antibacterial agent | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |
| WO-1991014687-A1 | 2-(SUBSTITUTED PYRROLIDINYLTHIO)CARBAPENEM DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-10-03 | — | — | WO | disclosed |
| EP-0449191-A1 | 2-(Substituted pyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-10-02 | — | — | EP | disclosed |