Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11135619 | 0.83 | CA12 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL21965864 | 0.80 | GAA (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5014888 | 0.78 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL26552434 | 0.78 | ALDH1A1 (0.42) | GAAKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL8944108 | 0.78 | CA1 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6073435 | 0.77 | CYP19A1 (0.45) | KDM4EPOLBMCOLN3ALDH1A1MAPT | |
| SCHEMBL14925281 | 0.77 | KMT2A (0.46) | HTTMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL31178319 | 0.77 | CYP19A1 (0.45) | KDM4EPOLBMCOLN3ALDH1A1MAPT | |
| SCHEMBL24662564 | 0.77 | ALDH1A1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8138311 | 0.77 | CYP1A2 (0.43) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3273998-B1 | MAYTANSINOID DERIVATIVES, CONJUGATES THEREOF, AND METHODS OF USE | REGENERON PHARMA (US) | 2019-09-04 | — | — | EP | disclosed |
| US-5532138-A | Method and kits for determining peroxidatively active catalysts | BEHRINGWERKE AG (DE) | 1996-07-02 | — | — | US | disclosed |