Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.67 |
| ▸ | PPARG | P37231 | 4/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694817 | 0.88 | TAAR1 (0.69) | ACACBTAAR1SIGMAR1NPC1RAB9A | |
| SCHEMBL16541091 | 0.87 | SIGMAR1 (0.60) | ACACBPPARGSIGMAR1MAOBLTA4H | |
| SCHEMBL16552348 | 0.84 | ACACB (0.63) | ACACBPPARGSIGMAR1MAOBLTA4H | |
| SCHEMBL20943572 | 0.84 | ACACB (0.63) | ACACBPPARGSIGMAR1MAOBLTA4H | |
| SCHEMBL1123162 | 0.83 | ACACB (0.67) | ACACBSIGMAR1MAOBNPC1RAB9A | |
| SCHEMBL12001666 | 0.82 | ACACB (0.82) | ACACB | |
| SCHEMBL8416595 | 0.82 | MAOB (0.56) | PPARGMAOBLTA4HMMEACE | |
| SCHEMBL19930027 | 0.80 | BCL2 (0.59) | PPARGSIGMAR1MAOBLTA4HMME | |
| SCHEMBL12532786 | 0.80 | BCL2 (0.59) | PPARGSIGMAR1MAOBLTA4HMME | |
| SCHEMBL11211220 | 0.80 | ALOX5 (0.54) | ACACBPPARGSIGMAR1MAOBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |