Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020833 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL9020836 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL9327584 | 0.91 | PIK3CG (0.42) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL9416058 | 0.91 | CTDSP1 (0.41) | KDM4EALDH1A1LMNAHPGDMAPT | |
| SCHEMBL9416077 | 0.83 | CTDSP1 (0.41) | KDM4EALDH1A1LMNAHPGDCTDSP1 | |
| SCHEMBL9021173 | 0.82 | L3MBTL1 (0.52) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL9329792 | 0.82 | L3MBTL1 (0.52) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL8880532 | 0.80 | MAPT (0.56) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL1387672 | 0.80 | MAPT (0.56) | KDM4EALDH1A1PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL9021420 | 0.79 | KDM4E (0.52) | KDM4EALDH1A1PIK3CGLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335297-B1 | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-13 | — | — | EP | claimed |
| US-5336768-A | Bactericides | HOFFMANN-LA ROCHE INC. (US) | 1994-08-09 | — | — | US | disclosed |