Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021173 | 1.00 | L3MBTL1 (0.52) | L3MBTL1PIK3CGKDM4EALDH1A1PIK3CD | |
| SCHEMBL9021139 | 0.93 | PIK3CG (0.47) | L3MBTL1PIK3CGKDM4EALDH1A1PIK3CD | |
| SCHEMBL8192526 | 0.92 | L3MBTL1 (0.46) | L3MBTL1PIK3CGKDM4EALDH1A1PIK3CD | |
| SCHEMBL9022337 | 0.91 | L3MBTL1 (0.53) | L3MBTL1PIK3CGKDM4EALDH1A1PIK3CD | |
| SCHEMBL8880532 | 0.89 | MAPT (0.56) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 | |
| SCHEMBL1387672 | 0.89 | MAPT (0.56) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 | |
| SCHEMBL9022340 | 0.83 | KDM4E (0.50) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 | |
| SCHEMBL9743994 | 0.82 | L3MBTL1 (0.54) | L3MBTL1KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL9020841 | 0.82 | KDM4E (0.46) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 | |
| SCHEMBL9020836 | 0.82 | KDM4E (0.46) | PIK3CGKDM4EALDH1A1PIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336768-A | Bactericides | HOFFMANN-LA ROCHE INC. (US) | 1994-08-09 | — | — | US | claimed |
| US-5336768-A | Bactericides | HOFFMANN-LA ROCHE INC. (US) | 1994-08-09 | — | — | US | disclosed |