Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FABP2 | P12104 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 3/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021148 | 0.85 | TP53 (0.45) | TP53MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7877299 | 0.78 | TP53 (0.40) | TP53NPC1RAB9AESRRGMAPT | |
| SCHEMBL9021042 | 0.69 | TAAR1 (0.41) | MEN1KMT2A | |
| SCHEMBL7875247 | 0.69 | ESRRG (0.42) | TP53MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9021085 | 0.69 | TP53 (0.44) | TP53MAPTALDH1A1GAA | |
| SCHEMBL9020794 | 0.68 | NR1H2 (0.34) | TP53MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9020699 | 0.67 | CNR1 (0.37) | GAA | |
| SCHEMBL9021078 | 0.66 | PRCP (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL9062813 | 0.65 | KMT2A (0.53) | MEN1KMT2AGAA | |
| SCHEMBL9062823 | 0.65 | KMT2A (0.53) | MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |