Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021148 | 0.83 | TP53 (0.45) | TP53ALDH1A1GAAMAPTTMEM97 | |
| SCHEMBL9020794 | 0.81 | NR1H2 (0.34) | TP53ALDH1A1GAALMNAMAPT | |
| SCHEMBL9020952 | 0.79 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL7876986 | 0.77 | ALDH1A1 (0.41) | TP53ALDH1A1GAAPRMT1THRB | |
| SCHEMBL7879555 | 0.75 | TDP1 (0.47) | ALDH1A1LMNAMAPTTBXAS1TBXA2R | |
| SCHEMBL9369023 | 0.75 | NPSR1 (0.33) | — | |
| SCHEMBL9020699 | 0.71 | CNR1 (0.37) | GAATHRB | |
| SCHEMBL9020867 | 0.69 | TP53 (0.42) | TP53ALDH1A1GAAMAPT | |
| SCHEMBL9368177 | 0.67 | NAMPT (0.43) | TBXAS1CYP19A1 | |
| SCHEMBL9021078 | 0.67 | PRCP (0.39) | ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |