Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | HAT1 | O14929 | 4/20 | 0.32 |
| ▸ | EP300 | Q09472 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021148 | 0.74 | TP53 (0.45) | GAA | |
| SCHEMBL9020794 | 0.74 | NR1H2 (0.34) | CNR1CNR2GAAHTT | |
| SCHEMBL5924557 | 0.71 | SMN1; SMN2 (0.46) | HTT | |
| SCHEMBL9021085 | 0.71 | TP53 (0.44) | GAATHRB | |
| SCHEMBL7879542 | 0.69 | KDM4E (0.45) | KDM4EHTT | |
| SCHEMBL9369023 | 0.69 | NPSR1 (0.33) | — | |
| SCHEMBL9020867 | 0.67 | TP53 (0.42) | GAA | |
| SCHEMBL9368177 | 0.65 | NAMPT (0.43) | — | |
| SCHEMBL8949535 | 0.65 | NPSR1 (0.34) | CNR1CNR2 | |
| SCHEMBL9595179 | 0.65 | BRS3 (0.38) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705251-A1 | IMIDAZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |