Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060209 | 0.77 | TSHR (0.56) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL5057282 | 0.77 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2732425 | 0.76 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3850342 | 0.75 | TSHR (0.48) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL10033079 | 0.75 | TSHR (0.53) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27856672 | 0.74 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29550542 | 0.74 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL34661 | 0.74 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9103359 | 0.74 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL9218927 | 0.73 | TSHR (0.47) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456250-B1 | POLY(VINYLALCOHOL),CO-POLY(VINYLAMINE) POLYMERS COMPRISING FUNCTIOAL MOIETIES | CIBA HOLDING INC (CH) | 2009-01-14 | — | — | EP | claimed |
| WO-2012042157-A1 | GEL PROCESS FOR POLYMERIZATION VIA ULTRASOUND INITIATION | UPPA - UNIVERSITÉ DE PAU ET DES PAYS DE L'ADOUR (FR) | 2012-04-05 | — | — | WO | disclosed |