Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074375 | 0.91 | GAA (0.38) | GAACDK1KDM4ENPC1ALDH1A1 | |
| SCHEMBL9021912 | 0.87 | GAA (0.38) | GAACDK1KDM4ENPC1ALDH1A1 | |
| SCHEMBL10506658 | 0.82 | NPC1 (0.42) | GAACDK1KDM4ENPC1ALDH1A1 | |
| SCHEMBL9021875 | 0.79 | GAA (0.36) | GAACDK1KDM4ENPC1ALDH1A1 | |
| SCHEMBL8530141 | 0.78 | ALDH1A1 (0.40) | GAACDK1KDM4ENPC1ALDH1A1 | |
| SCHEMBL10508148 | 0.75 | NPC1 (0.45) | GAACDK1KDM4ENPC1ALDH1A1 | |
| SCHEMBL11177162 | 0.74 | NPC1 (0.43) | GAACDK1KDM4ENPC1ALDH1A1 | |
| SCHEMBL9022273 | 0.74 | GAA (0.34) | GAAKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL9037756 | 0.74 | GAA (0.37) | GAACDK1KDM4ENPC1ALDH1A1 | |
| SCHEMBL10755063 | 0.72 | GAA (0.39) | GAACDK1KDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546082-B1 | HERBICIDAL PYRROLESULFONYLUREAS | DU PONT (US) | 1996-12-18 | — | — | EP | claimed |
| EP-0546082-A1 | HERBICIDAL PYRROLESULFONYLUREAS. | DU PONT (US) | 1993-06-16 | — | — | EP | claimed |
| WO-1992004319-A1 | HERBICIDAL PYRROLESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-19 | — | — | WO | claimed |