Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022337 | 0.93 | L3MBTL1 (0.53) | KDM4EHTTHSD17B10KMT2AALDH1A1 | |
| SCHEMBL9021139 | 0.91 | PIK3CG (0.47) | KDM4EHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL9021423 | 0.88 | KDM4E (0.51) | KDM4EHTTHSD17B10KMT2AALDH1A1 | |
| SCHEMBL9021173 | 0.83 | L3MBTL1 (0.52) | KDM4EHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL9329792 | 0.83 | L3MBTL1 (0.52) | KDM4EHSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL9743438 | 0.83 | L3MBTL1 (0.53) | KDM4EHTTHSD17B10KMT2AALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL9022988 | 0.83 | HSD17B10 (0.52) | KDM4EHTTHSD17B10KMT2AALDH1A1 | |
| SCHEMBL9022061 | 0.83 | KDM4E (0.46) | KDM4EHTTHSD17B10KMT2AALDH1A1 | |
| SCHEMBL9745641 | 0.83 | L3MBTL1 (0.52) | KDM4EHTTHSD17B10KMT2AALDH1A1 | |
| SCHEMBL9745653 | 0.83 | L3MBTL1 (0.52) | KDM4EHTTHSD17B10KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335297-B1 | Cephalosporin derivatives | HOFFMANN LA ROCHE (CH) | 1996-03-13 | — | — | EP | disclosed |